Audio & Entertainment / Recording
Last updated: Written by: Rafael Rocha

The 5 Best Audio Interfaces for Guitar by Recording Setup

Plugging a guitar straight into a laptop's headphone jack is an easy way to make an amp-sim setup harder than it needs to be. What you want is a proper high-impedance instrument input, a headphone path you can monitor without distracting delay, and enough inputs for the way you actually record. One guitar at a time is a different purchase from a guitar-and-vocal session.

My starting pick is the Scarlett Solo 4th Gen: one Hi-Z instrument input and a separate mic preamp cover a common home-recording desk. The Audient iD4 is for someone who prioritizes its monitor controls, while the MiniFuse 1 cuts the footprint and cost. If two microphones or two instruments must record together, skip every one-input promise and check the Scarlett 2i2 instead.

Our top 5 audio interfaces for guitar by recording setup

Swipe to compare price, rating and best use →

Five products compared by price, rating and best use.
ProductPriceRatingBest for
01Focusrite Scarlett Solo 4th Gen USB-C Audio Interface | 1 XLR Mic Preamp, 1 Hi-Z Instrument Input, 24-Bit/192kHz, 120dB Dynamic Range, Air Modes, PC/Mac/iPad Compatible product image from AmazonFocusrite Scarlett Solo 4th GenDetails ↓$159.99
4.6/5Amazon
Best guitar-and-vocal starter
02Audient Audio Interface iD4 MKII, Class A Console Microphone Preamp (High Speed USB-C, Monitor Mix and Monitor Panning Function, 2 Headphone Outputs, Mac/PC/iOS Compatible), Black product image from AmazonAudient iD4 MKIIDetails ↓$179.99
4.5/5Amazon
Best hands-on monitor control
03Arturia MiniFuse USB Audio & MIDI Interface, MiniFuse 1 | Record voice guitar and synths, best-in-class sound specs, pair with any microphone, Ableton Live Lite, 5-year warranty product image from AmazonArturia MiniFuse 1Details ↓$119.00
4.7/5Amazon
Best small single-input desk
04Audient EVO 4 USB Audio Interface product image from AmazonEVO Audient EVO 4Details ↓$158.00
4.4/5Amazon
Best guided gain setup
05Universal Audio Volt 1 USB Audio Interface product image from AmazonUniversal Audio Volt 1Details ↓$139.00
4.6/5Amazon
Best vintage-voiced option
Focusrite Scarlett Solo 4th Gen USB-C Audio Interface | 1 XLR Mic Preamp, 1 Hi-Z Instrument Input, 24-Bit/192kHz, 120dB Dynamic Range, Air Modes, PC/Mac/iPad Compatible product image from Amazon

01 — Focusrite

Best guitar-and-vocal starter

Scarlett Solo 4th Gen

4.6/5Amazon
$159.99In Stock

The Scarlett Solo 4th Gen separates its front Hi-Z guitar input from the rear XLR microphone input. That layout makes a simple electric-guitar-and-vocal recording setup possible without repatching one combo jack. You still get one mic preamp, so a two-microphone session needs a different interface.

I put it first because the physical input layout matches the most common solo musician's next step, not just the first guitar take. iD4 has a strong monitor-control case and MiniFuse 1 is cheaper, but neither replaces the Solo's straightforward separate guitar and mic path for this buyer.

Specifications: Focusrite Scarlett Solo hardware guide ↗

View on Amazon ↗
Choose it if

One guitar plus one microphone.

Skip it if

You need two mic preamps.

What I like

+Separate Hi-Z and XLR paths.

What to weigh

−Only one microphone preamp.

Audient Audio Interface iD4 MKII, Class A Console Microphone Preamp (High Speed USB-C, Monitor Mix and Monitor Panning Function, 2 Headphone Outputs, Mac/PC/iOS Compatible), Black product image from Amazon

02 — Audient

Best hands-on monitor control

Audient iD4 MKII

4.5/5Amazon
$179.99In Stock

Audient's iD4 MKII pairs a microphone preamp with a dedicated instrument input and a prominent monitor control. Its headphone and speaker workflow suits a guitarist who records near studio monitors and wants tactile level changes. It is still a compact two-channel desk interface, not a multi-mic band recorder.

Second place reflects that monitoring ergonomics can matter every day, but the Solo has a lower-friction default input layout at its current offer. I would move iD4 to first for a buyer who specifically values its large monitor knob and Audient's desktop workflow.

Specifications: Exact Amazon product listing ↗

View on Amazon ↗
Choose it if

Guitar recording at a monitor-speaker desk.

Skip it if

You need several simultaneous microphones.

What I like

+Dedicated instrument path and monitor dial.

What to weigh

−Small input count for a band.

Mic inputs
1
Instrument inputs
1 JFET
Arturia MiniFuse USB Audio & MIDI Interface, MiniFuse 1 | Record voice guitar and synths, best-in-class sound specs, pair with any microphone, Ableton Live Lite, 5-year warranty product image from Amazon

03 — Arturia

Best small single-input desk

Arturia MiniFuse 1

4.7/5Amazon
$119.00In Stock

MiniFuse 1 keeps the desk footprint small with one combo input that can accept guitar or microphone, plus loopback and a USB hub connection. That is a useful bargain for overdubbing one part at a time or sending computer audio into a stream. The single input means guitar and vocal cannot be captured independently together.

I rank it third for the player who works in layers. It costs less than the first two and offers a clever loopback path, but its one-input limit is a real reason to pay for the Scarlett Solo if simultaneous singing and playing is central.

Specifications: Arturia MiniFuse 1 product details ↗

View on Amazon ↗
Choose it if

Overdubbing one instrument at a time.

Skip it if

You need guitar and voice on separate tracks together.

What I like

+Compact interface with loopback.

What to weigh

−Only one recording input.

Mic inputs
1
Loopback
Yes
Audient EVO 4 USB Audio Interface product image from Amazon

04 — EVO

Best guided gain setup

Audient EVO 4

4.4/5Amazon
$158.00In Stock

EVO 4 offers two combo inputs, instrument recording and Audient's Smartgain setup. It fits a guitarist who switches between a mic and instrument and would appreciate help setting initial levels. The controls are more menu-like than the iD4's traditional monitor knob, which may slow someone who wants direct hardware access.

Fourth is for a buyer who wants two-input flexibility and assisted gain more than a familiar control surface. I place the Solo higher for its obvious guitar-plus-mic layout and iD4 higher for monitor ergonomics; EVO 4 remains a distinct workflow choice.

Specifications: Exact Amazon product listing ↗

View on Amazon ↗
Choose it if

A two-input setup with assisted levels.

Skip it if

You prefer dedicated controls for each action.

What I like

+Smartgain and two combo inputs.

What to weigh

−Less direct tactile control than iD4.

Mic inputs
2
Features
Smartgain / loopback
Universal Audio Volt 1 USB Audio Interface product image from Amazon

05 — Universal Audio

Best vintage-voiced option

Universal Audio Volt 1

4.6/5Amazon
$139.00In Stock

Volt 1 gives a single combo input with a Hi-Z instrument mode and a switchable vintage preamp character. That makes it appealing for one guitar take at a time, especially if you like shaping the input before the amp simulation. A one-input box cannot record a separate vocal microphone simultaneously.

I leave Volt 1 fifth because its character feature is a preference, not a universal guitar advantage. For a player recording one source at a time it may be the most enjoyable choice; for the broader home musician I would buy the Solo's separate inputs first.

Specifications: Universal Audio Volt 1 product details ↗

View on Amazon ↗
Choose it if

One-at-a-time guitar takes with input color.

Skip it if

You record guitar and vocals together.

What I like

+Switchable vintage preamp mode.

What to weigh

−One input limits simultaneous recording.

Mic inputs
1
Resolution
24-bit / 192 kHz
Price information

Amazon price and availability checked Oct 18, 2026, 9:01 AM Lisbon time. Prices and availability are subject to change; the information shown on Amazon.com at purchase applies.

Our process

How we picked.

We compare five relevant products for different needs, using documented specifications, clear use cases and practical trade-offs. Our goal is to make the differences clear and help you choose with confidence.

  • 01
    Relevance

    Each product must fit the guide’s intended use, audience and requirements.

  • 02
    Specifications

    We compare the key product details that meaningfully affect the buying decision.

  • 03
    Use case and fit

    We compare the intended use, configuration and practical fit of every selected product.

  • 04
    Strengths and limitations

    We explain where each option performs best and the compromises to consider.

Read our full methodology →

Good questions

FAQ — Audio Interfaces for Guitar by Recording Setup

01What is a Hi-Z input?+

It is an instrument input designed for the signal from a passive guitar or bass pickup. Check that the exact interface has one rather than assuming every audio input behaves the same way.

02Can I record guitar and vocals at the same time?+

The Scarlett Solo has a dedicated guitar input and an XLR mic input. Other one-input models in this list cannot take two independent sources at once; check input layout before buying.

The short answer

Start with the Scarlett Solo 4th Gen.

I recommend it for one guitar plus one microphone. Choose something else if you need two mic preamps.

View on Amazon ↗