5 Best Audio Interfaces with 4 Inputs
Five audio interfaces with 4 inputs, including MOTU and Focusrite, compared by simultaneous input count, preamps and monitoring.
Our top 5 audio interfaces with 4 inputs
Swipe to compare price, rating and best use →
| Product | Price | Rating | Best for |
|---|---|---|---|
01 Motu M4 4x4 USB-C Audio InterfaceDetails ↓ | $279.95 | 4.6/5Amazon | Best overall |
02 Focusrite Scarlett 4i4 4th Gen USB-C Audio InterfaceDetails ↓ | $309.99 | 4.7/5Amazon | Best for easy setup |
03 Zoom AMS-44 USB Audio Interface for Musicians & PodcastersDetails ↓ | $199.95 | 4.1/5Amazon | Best for more features |
04 Behringer U-PHORIA UMC404HD Audiophile 4x4Details ↓ | $139.00 | 4.6/5Amazon | Best for compact spaces |
05 Arturia MiniFuse USB Audio & MIDI InterfaceDetails ↓ | $249.00 | 4.6/5Amazon | Best value |
01 — MOTU
Best overallMotu M4 4x4 USB-C Audio Interface
Motu M4 4x4 USB-C Audio Interface has USB recording interface, at least four input channels, MIDI I/O. This configuration includes mixing and podcasting with 4x4 USB-C connectivity, MIDI I/O and low latency monitoring. A four-input interface records more microphones or instruments at once than a two-input unit. Count the actual analogue inputs on the exact model and check phantom power and driver support.
View on Amazon ↗Reasons to buy
+Motu M4 4x4 USB-C Audio Interface has USB recording interface, at least four input channels, MIDI I/O.
Reasons to avoid
−Count the actual analogue inputs on the exact model and check phantom power and driver support. Simultaneous input count, preamps and monitoring can vary by configuration.
02 — Focusrite
Best for easy setupFocusrite Scarlett 4i4 4th Gen USB-C Audio Interface
Focusrite Scarlett 4i4 4th Gen USB-C Audio Interface has USB recording interface, USB-C connection, 4-series model. A four-input interface records more microphones or instruments at once than a two-input unit. Count the actual analogue inputs on the exact model and check phantom power and driver support.
View on Amazon ↗Reasons to buy
+Focusrite Scarlett 4i4 4th Gen USB-C Audio Interface has USB recording interface, USB-C connection, 4-series model.
Reasons to avoid
−Count the actual analogue inputs on the exact model and check phantom power and driver support. Simultaneous input count, preamps and monitoring can vary by configuration.
03 — Zoom
Best for more featuresZoom AMS-44 USB Audio Interface for Musicians & Podcasters
Zoom AMS-44 USB Audio Interface for Musicians & Podcasters has USB recording interface, at least four input channels, 4-series model. A four-input interface records more microphones or instruments at once than a two-input unit. Count the actual analogue inputs on the exact model and check phantom power and driver support.
View on Amazon ↗Reasons to buy
+Zoom AMS-44 USB Audio Interface for Musicians & Podcasters has USB recording interface, at least four input channels, 4-series model.
Reasons to avoid
−Count the actual analogue inputs on the exact model and check phantom power and driver support. Simultaneous input count, preamps and monitoring can vary by configuration.
04 — Behringer
Best for compact spacesBehringer U-PHORIA UMC404HD Audiophile 4x4
Behringer U-PHORIA UMC404HD Audiophile 4x4 has at least four input channels, MIDI I/O, 4-series model. This configuration includes 24-Bit/192 kHz USB Audio/MIDI Interface with Midas Mic Preamplifiers. A four-input interface records more microphones or instruments at once than a two-input unit. Count the actual analogue inputs on the exact model and check phantom power and driver support.
View on Amazon ↗Reasons to buy
+Behringer U-PHORIA UMC404HD Audiophile 4x4 has at least four input channels, MIDI I/O, 4-series model.
Reasons to avoid
−Count the actual analogue inputs on the exact model and check phantom power and driver support. Simultaneous input count, preamps and monitoring can vary by configuration.
05 — Arturia
Best valueArturia MiniFuse USB Audio & MIDI Interface
Arturia MiniFuse USB Audio & MIDI Interface has MIDI I/O, MiniFuse 4 model, 4-series model. A four-input interface records more microphones or instruments at once than a two-input unit. Count the actual analogue inputs on the exact model and check phantom power and driver support.
View on Amazon ↗Reasons to buy
+Arturia MiniFuse USB Audio & MIDI Interface has MIDI I/O, MiniFuse 4 model, 4-series model.
Reasons to avoid
−Count the actual analogue inputs on the exact model and check phantom power and driver support. Simultaneous input count, preamps and monitoring can vary by configuration.
Price information
Amazon price and availability checked Oct 17, 2026, 10:23 PM Lisbon time. Prices and availability are subject to change; the information shown on Amazon.com at purchase applies.
Our process
How we picked.
We compare five relevant products for different needs, using documented specifications, clear use cases and practical trade-offs. Our goal is to make the differences clear and help you choose with confidence.
- 01Relevance
Each product must fit the guide’s intended use, audience and requirements.
- 02Specifications
We compare the key product details that meaningfully affect the buying decision.
- 03Use case and fit
We compare the intended use, configuration and practical fit of every selected product.
- 04Strengths and limitations
We explain where each option performs best and the compromises to consider.
Good questions
FAQ — Audio Interfaces with 4 Inputs
01What matters most when choosing audio interfaces with 4 inputs?+
Compare simultaneous input count, preamps and monitoring. A four-input interface records more microphones or instruments at once than a two-input unit.
02Which type of audio interfaces with 4 inputs fits everyday use?+
A four-input interface records more microphones or instruments at once than a two-input unit.
03How can I check the fit or compatibility of audio interfaces with 4 inputs?+
Count the actual analogue inputs on the exact model and check phantom power and driver support. Simultaneous input count, preamps and monitoring should match your intended use.
04When should I pay more for audio interfaces with 4 inputs?+
Pay more when a specific feature improves your own use. A four-input interface records more microphones or instruments at once than a two-input unit.
05How should I care for audio interfaces with 4 inputs?+
Count the actual analogue inputs on the exact model and check phantom power and driver support. Follow the maker's cleaning and storage directions for the exact model.
06What mistake should I avoid before buying audio interfaces with 4 inputs?+
Count the actual analogue inputs on the exact model and check phantom power and driver support. Compare the complete configuration and included parts, not the family name alone.
The short answer
Start with the Motu M4 4x4 USB-C Audio Interface.
It is our first pick for this guide’s exact scope. Choose another option when its stated use case or trade-off better matches yours.
View on Amazon ↗Keep looking
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